Pharmacokinetics
GHRP-2 is a synthetic analog to a compound active within the gut, namely met-enkaphalin. Met-enkaphalin targets a receptor in the gut, the ghrelin receptor, which regulates growth hormone release and hunger levels.[2][3] GHRP-2, being analogous to met-enkaphalin, also interacts with ghrelin, leading to probable increases in hunger and growth hormone release.[1]
Scientific Studies
GHRP-2 has been extensively tested in both human and animal test subjects. In a study on health and lean males, subjects were injected subcutaneously with GHRP-2 and instructed to eat at a buffet. Most non-placebo subjects were observed to have eaten substantially more than usual. Higher levels of human growth hormone were also found in those injected with GHRP-2.[1] Another study observed the effects of GHRP-2 on swine. Though appetite levels were within standard error margins, increased amounts of growth hormone were also observed in the subjects.[4]
Sources:
[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824650/
[2] https://www.sciencedirect.com/science/article/pii/S2212877815000605?via%3Dihub
[3] http://www.eurekaselect.com/118430/article
[4] https://www.ncbi.nlm.nih.gov/pubmed/10793268
[5] https://annals.org/aim/article-abstract/732002/systematic-review-safety-efficacy-growth-hormone-healthy-elderly?doi=10.7326%2f0003-4819-146-2-200701160-00005
[6] https://www.verywellhealth.com/injection-side-effects-call-doctor-2616542
